Characterization of population-based variation and putative functional elements for the multiple-cancer susceptibility loci at 5p15.33

Background: TERT encodes the telomerase reverse transcriptase, which is responsible for maintaining telomere ends by addition of (TTAGGG) (n) nucleotide repeats at the telomere.  Recent genome-wide association studies have found common genetic variants at the TERT-CLPTM1L locus (5p15.33) associated...

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Detalles Bibliográficos
Autores principales: Mirabello, Lisa, Chung, Charles C., Yeager, Meredith, Savage, Sharon A
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000Research 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654438/
https://www.ncbi.nlm.nih.gov/pubmed/26664699
http://dx.doi.org/10.12688/f1000research.5186.1

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