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Pooled Sequencing of Candidate Genes Implicates Rare Variants in the Development of Asthma Following Severe RSV Bronchiolitis in Infancy

Severe infection with respiratory syncytial virus (RSV) during infancy is strongly associated with the development of asthma. To identify genetic variation that contributes to asthma following severe RSV bronchiolitis during infancy, we sequenced the coding exons of 131 asthma candidate genes in 182...

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Detalles Bibliográficos
Autores principales: Torgerson, Dara G., Giri, Tusar, Druley, Todd E., Zheng, Jie, Huntsman, Scott, Seibold, Max A., Young, Andrew L., Schweiger, Toni, Yin-Declue, Huiqing, Sajol, Geneline D., Schechtman, Kenneth B, Hernandez, Ryan D., Randolph, Adrienne G., Bacharier, Leonard B., Castro, Mario
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654486/
https://www.ncbi.nlm.nih.gov/pubmed/26587832
http://dx.doi.org/10.1371/journal.pone.0142649