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Developing Fast Fluorescent Protein Voltage Sensors by Optimizing FRET Interactions

FRET (Förster Resonance Energy Transfer)-based protein voltage sensors can be useful for monitoring neuronal activity in vivo because the ratio of signals between the donor and acceptor pair reduces common sources of noise such as heart beat artifacts. We improved the performance of FRET based genet...

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Detalles Bibliográficos
Autores principales: Sung, Uhna, Sepehri-Rad, Masoud, Piao, Hong Hua, Jin, Lei, Hughes, Thomas, Cohen, Lawrence B., Baker, Bradley J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654489/
https://www.ncbi.nlm.nih.gov/pubmed/26587834
http://dx.doi.org/10.1371/journal.pone.0141585

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