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Early Gelatinase Activity Is Not a Determinant of Long-Term Recovery after Traumatic Brain Injury in the Immature Mouse
The gelatinases, matrix metalloproteinases (MMP)-2 and MMP-9, are thought to be key mediators of secondary damage in adult animal models of brain injury. Moreover, an acute increase in these proteases in plasma and brain extracellular fluid of adult patients with moderate-to-severe traumatic brain i...
Autores principales: | Semple, Bridgette D., Noble-Haeusslein, Linda J., Gooyit, Major, Tercovich, Kayleen G., Peng, Zhihong, Nguyen, Trung T., Schroeder, Valerie A., Suckow, Mark A., Chang, Mayland, Raber, Jacob, Trivedi, Alpa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654502/ https://www.ncbi.nlm.nih.gov/pubmed/26588471 http://dx.doi.org/10.1371/journal.pone.0143386 |
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