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The Possible Mechanism of Advanced Glycation End Products (AGEs) for Alzheimer’s Disease

Amyloid precursor protein (APP) has been modified by β and γ-secretase that cause amyloid deposits (plaques) in neuronal cells. Glyceraldhyde-derived AGEs has been identified as a major source of neurotoxicity in Alzheimer’s disease (AD). In a previous study, we demonstrated that glyceraldehyde-deri...

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Detalles Bibliográficos
Autores principales:	Ko, Shun-Yao, Ko, Hshin-An, Chu, Kuo-Hsiung, Shieh, Tzong-Ming, Chi, Tzong-Cherng, Chen, Hong-I, Chang, Weng-Cheng, Chang, Shu-Shing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654523/ https://www.ncbi.nlm.nih.gov/pubmed/26587989 http://dx.doi.org/10.1371/journal.pone.0143345

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