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Activation of Type I and III Interferon Response by Mitochondrial and Peroxisomal MAVS and Inhibition by Hepatitis C Virus

Sensing viruses by pattern recognition receptors (PRR) triggers the innate immune system of the host cell and activates immune signaling cascades such as the RIG-I/IRF3 pathway. Mitochondrial antiviral-signaling protein (MAVS, also known as IPS-1, Cardif, and VISA) is the crucial adaptor protein of...

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Detalles Bibliográficos
Autores principales:	Bender, Silke, Reuter, Antje, Eberle, Florian, Einhorn, Evelyne, Binder, Marco, Bartenschlager, Ralf
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654527/ https://www.ncbi.nlm.nih.gov/pubmed/26588843 http://dx.doi.org/10.1371/journal.ppat.1005264

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