Dendritic Cell-Specific Deletion of β-Catenin Results in Fewer Regulatory T-Cells without Exacerbating Autoimmune Collagen-Induced Arthritis

Dendritic cells (DCs) are professional antigen presenting cells that have the dual ability to stimulate immunity and maintain tolerance. However, the signalling pathways mediating tolerogenic DC function in vivo remain largely unknown. The β-catenin pathway has been suggested to promote a regulatory...

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Detalles Bibliográficos
Autores principales: Alves, C. Henrique, Ober-Blöbaum, Julia L., Brouwers-Haspels, Inge, Asmawidjaja, Patrick S., Mus, Adriana M. C., Razawy, Wida, Molendijk, Marlieke, Clausen, Björn E., Lubberts, Erik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654567/
https://www.ncbi.nlm.nih.gov/pubmed/26587585
http://dx.doi.org/10.1371/journal.pone.0142972

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