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Conditional Expression of E2A-HLF Induces B-Cell Precursor Death and Myeloproliferative-Like Disease in Knock-In Mice

Chromosomal translocations are driver mutations of human cancers, particularly leukemias. They define disease subtypes and are used as prognostic markers, for minimal residual disease monitoring and therapeutic targets. Due to their low incidence, several translocations and their biological conseque...

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Detalles Bibliográficos
Autores principales:	Duque-Afonso, Jesús, Smith, Kevin S., Cleary, Michael L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654581/ https://www.ncbi.nlm.nih.gov/pubmed/26588248 http://dx.doi.org/10.1371/journal.pone.0143216

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