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Combined Use of Etomidate and Dexmedetomidine Produces an Additive Effect in Inhibiting the Secretion of Human Adrenocortical Hormones

BACKGROUND: The direct effects of etomidate were investigated on the secretion of cortisol and its precursors by dispersed cells from the adrenal cortex of human of animals. Dexmedetomidine (DEX) is an anesthetic agent that may interfere with cortisol secretion via an unknown mechanism, such as invo...

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Detalles Bibliográficos
Autores principales: Gu, Hongbin, Zhang, Mazhong, Cai, Meihua, Liu, Jinfen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: International Scientific Literature, Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654590/
https://www.ncbi.nlm.nih.gov/pubmed/26568275
http://dx.doi.org/10.12659/MSM.894728