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Matrix Elasticity of Void-Forming Hydrogels Controls Transplanted Stem Cell-Mediated Bone Formation
The effectiveness of stem-cell therapies has been hampered by cell death and limited control over fate(1). These problems can be partially circumvented by using macroporous biomaterials that improve the survival of transplanted stem cells and provide molecular cues to direct cell phenotype(2–4). Ste...
Autores principales: | Huebsch, Nathaniel, Lippens, Evi, Lee, Kangwon, Mehta, Manav, Koshy, Sandeep T, Darnell, Max C, Desai, Rajiv, Madl, Christopher M., Xu, Maria, Zhao, Xuanhe, Chaudhuri, Ovijit, Verbeke, Catia, Kim, Woo Seob, Alim, Karen, Mammoto, Akiko, Ingber, Donald E., Duda, Georg N, Mooney, David J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654683/ https://www.ncbi.nlm.nih.gov/pubmed/26366848 http://dx.doi.org/10.1038/nmat4407 |
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