Cargando…
Modified mRNA as a new therapeutic option for pediatric respiratory diseases and hemoglobinopathies
BACKGROUND: The immunogenicity and limited stability of conventional messenger RNA (mRNA) has traditionally restricted its potential therapeutic use. In 1992, the first clinical application of mRNA was reported as a potential protein-replacement therapy; however, subsequent investigations have not b...
| Autores principales: | , , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2015
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654728/ https://www.ncbi.nlm.nih.gov/pubmed/26589812 http://dx.doi.org/10.1186/s40348-015-0022-6 |