Tracking CNS and systemic sources of oxidative stress during the course of chronic neuroinflammation

The functional dynamics and cellular sources of oxidative stress are central to understanding MS pathogenesis but remain elusive, due to the lack of appropriate detection methods. Here we employ NAD(P)H fluorescence lifetime imaging to detect functional NADPH oxidases (NOX enzymes) in vivo to identi...

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Detalles Bibliográficos
Autores principales: Mossakowski, Agata A., Pohlan, Julian, Bremer, Daniel, Lindquist, Randall, Millward, Jason M., Bock, Markus, Pollok, Karolin, Mothes, Ronja, Viohl, Leonard, Radbruch, Moritz, Gerhard, Jenny, Bellmann-Strobl, Judith, Behrens, Janina, Infante-Duarte, Carmen, Mähler, Anja, Boschmann, Michael, Rinnenthal, Jan Leo, Füchtemeier, Martina, Herz, Josephine, Pache, Florence C., Bardua, Markus, Priller, Josef, Hauser, Anja E., Paul, Friedemann, Niesner, Raluca, Radbruch, Helena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2015
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654749/
https://www.ncbi.nlm.nih.gov/pubmed/26521072
http://dx.doi.org/10.1007/s00401-015-1497-x

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