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Identification of global regulators of T-helper cell lineage specification

BACKGROUND: Activation and differentiation of T-helper (Th) cells into Th1 and Th2 types is a complex process orchestrated by distinct gene activation programs engaging a number of genes. This process is crucial for a robust immune response and an imbalance might lead to disease states such as autoi...

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Detalles Bibliográficos
Autores principales:	Kanduri, Kartiek, Tripathi, Subhash, Larjo, Antti, Mannerström, Henrik, Ullah, Ubaid, Lund, Riikka, Hawkins, R. David, Ren, Bing, Lähdesmäki, Harri, Lahesmaa, Riitta
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654807/ https://www.ncbi.nlm.nih.gov/pubmed/26589177 http://dx.doi.org/10.1186/s13073-015-0237-0

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