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Quantitative analysis of chromatin interaction changes upon a 4.3 Mb deletion at mouse 4E2
BACKGROUND: Circular chromosome conformation capture (4C) has provided important insights into three dimensional (3D) genome organization and its critical impact on the regulation of gene expression. We developed a new quantitative framework based on polymer physics for the analysis of paired-end se...
Autores principales: | , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654810/ https://www.ncbi.nlm.nih.gov/pubmed/26589460 http://dx.doi.org/10.1186/s12864-015-2137-5 |