Cargando…
Vps34 and PLD1 take center stage in nutrient signaling: their dual roles in regulating autophagy
Autophagy is a critical pathway leading to lysosomal degradation of cellular components in response to changes in nutrient availability. Autophagy includes the biogenesis of autophagosomes and their sequential maturation through fusion with endo-lysosomes. The class III PI3 kinase Vps34 and its prod...
Autor principal: | Yoon, Mee-Sup |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654845/ https://www.ncbi.nlm.nih.gov/pubmed/26589724 http://dx.doi.org/10.1186/s12964-015-0122-x |
Ejemplares similares
-
Phosphoproteomic identification of ULK substrates reveals VPS15‐dependent ULK/VPS34 interplay in the regulation of autophagy
por: Mercer, Thomas John, et al.
Publicado: (2021) -
Aurone derivatives as Vps34 inhibitors that modulate autophagy
por: Li, Guodong, et al.
Publicado: (2019) -
PLD1 regulates adipogenic differentiation through mTOR - IRS-1 phosphorylation at serine 636/639
por: Song, Hae-In, et al.
Publicado: (2016) -
The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling in Drosophila
por: Juhász, Gábor, et al.
Publicado: (2008) -
Ubiquitination of the PI3-kinase VPS-34 promotes VPS-34 stability and phagosome maturation
por: Liu, Jinchao, et al.
Publicado: (2018)