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Reconstruction of gene networks using prior knowledge
BACKGROUND: Reconstructing gene regulatory networks (GRNs) from expression data is a challenging task that has become essential to the understanding of complex regulatory mechanisms in cells. The major issues are the usually very high ratio of number of genes to sample size, and the noise in the ava...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654848/ https://www.ncbi.nlm.nih.gov/pubmed/26589494 http://dx.doi.org/10.1186/s12918-015-0233-4 |