Cargando…

Experimental infection of a US spike-insertion deletion porcine epidemic diarrhea virus in conventional nursing piglets and cross-protection to the original US PEDV infection

Although the original US porcine epidemic diarrhea virus (PEDV) was confirmed as highly virulent by multiple studies, the virulence of spike-insertion deletion (S-INDEL) PEDV strains is undefined. In this study, 3–4 day-old conventional suckling piglets were inoculated with S-INDEL PEDV Iowa106 (4 p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lin, Chun-Ming, Annamalai, Thavamathi, Liu, Xinsheng, Gao, Xiang, Lu, Zhongyan, El-Tholoth, Mohamed, Hu, Hui, Saif, Linda J., Wang, Qiuhong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2015
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4654902/ https://www.ncbi.nlm.nih.gov/pubmed/26589292 http://dx.doi.org/10.1186/s13567-015-0278-9

Ejemplares similares

Cross protective immune responses in nursing piglets infected with a US spike-insertion deletion porcine epidemic diarrhea virus strain and challenged with an original US PEDV strain
por: Annamalai, Thavamathi, et al.
Publicado: (2017)

Comparative pathogenesis of US porcine epidemic diarrhea virus (PEDV) strain PC21A in conventional 9-day-old nursing piglets vs. 26-day-old weaned pigs
por: Jung, Kwonil, et al.
Publicado: (2015)

Determination of the infectious titer and virulence of an original US porcine epidemic diarrhea virus PC22A strain
por: Liu, Xinsheng, et al.
Publicado: (2015)

Structural alteration of tight and adherens junctions in villous and crypt epithelium of the small and large intestine of conventional nursing piglets infected with porcine epidemic diarrhea virus
por: Jung, Kwonil, et al.
Publicado: (2015)

Age-dependent variation in innate immune responses to porcine epidemic diarrhea virus infection in suckling versus weaned pigs
por: Annamalai, Thavamathi, et al.
Publicado: (2015)

Porcine epidemic diarrhea virus (PEDV): An update on etiology, transmission, pathogenesis, and prevention and control
por: Jung, Kwonil, et al.
Publicado: (2020)

Pathology of US Porcine Epidemic Diarrhea Virus Strain PC21A in Gnotobiotic Pigs
por: Jung, Kwonil, et al.
Publicado: (2014)

Reverse transcription-PCR assays for the differentiation of various US porcine epidemic diarrhea virus strains
por: Liu, Xinsheng, et al.
Publicado: (2016)

Virtual Screening-Based Peptides Targeting Spike Protein to Inhibit Porcine Epidemic Diarrhea Virus (PEDV) Infection
por: Xu, Qian, et al.
Publicado: (2023)

The enhanced replication of an S-intact PEDV during coinfection with an S1 NTD-del PEDV in piglets
por: Su, Yunfang, et al.
Publicado: (2019)

A flagellin-adjuvanted inactivated porcine epidemic diarrhea virus (PEDV) vaccine provides enhanced immune protection against PEDV challenge in piglets
por: Xu, Xiangwei, et al.
Publicado: (2020)

Novel Porcine Epidemic Diarrhea Virus (PEDV) Variants with Large Deletions in the Spike (S) Gene Coexist with PEDV Strains Possessing an Intact S Gene in Domestic Pigs in Japan: A New Disease Situation
por: Diep, Nguyen Van, et al.
Publicado: (2017)

Cell culture isolation and sequence analysis of genetically diverse US porcine epidemic diarrhea virus strains including a novel strain with a large deletion in the spike gene
por: Oka, Tomoichiro, et al.
Publicado: (2014)

Attenuation of an original US porcine epidemic diarrhea virus strain PC22A via serial cell culture passage
por: Lin, Chun-Ming, et al.
Publicado: (2017)

Lactogenic immunity and vaccines for porcine epidemic diarrhea virus (PEDV): Historical and current concepts
por: Langel, Stephanie N., et al.
Publicado: (2016)

Sequence and phylogenetic analysis of nucleocapsid genes of porcine epidemic diarrhea virus (PEDV) strains in China
por: Li, Zhili, et al.
Publicado: (2013)

Molecular characterization of US-like and Asian non-S INDEL strains of porcine epidemic diarrhea virus (PEDV) that circulated in Japan during 2013–2016 and PEDVs collected from recurrent outbreaks
por: Van Diep, Nguyen, et al.
Publicado: (2018)

Immune responses to porcine epidemic diarrhea virus (PEDV) in swine and protection against subsequent infection
por: Krishna, Venkatramana D., et al.
Publicado: (2020)

Immunohistochemical detection of the vomiting-inducing monoamine neurotransmitter serotonin and enterochromaffin cells in the intestines of conventional or gnotobiotic (Gn) pigs infected with porcine epidemic diarrhea virus (PEDV) and serum cytokine responses of Gn pigs to acute PEDV infection
por: Jung, Kwonil, et al.
Publicado: (2018)

Genetic characterization of the spike gene of porcine epidemic diarrhea viruses (PEDVs) circulating in Vietnam from 2015 to 2016
por: Than, Van T., et al.
Publicado: (2020)

The Carboxy Terminal Region on Spike Protein of Porcine Epidemic Diarrhea Virus (PEDV) Is Important for Evaluating Neutralizing Activity
por: Kang, Ki-Jong, et al.
Publicado: (2021)

Monitoring Survivability and Infectivity of Porcine Epidemic Diarrhea Virus (PEDv) in the Infected On-Farm Earthen Manure Storages (EMS)
por: Tun, Hein M., et al.
Publicado: (2016)

Derivation of attenuated porcine epidemic diarrhea virus (PEDV) as vaccine candidate
por: Kweon, Chang-Hee, et al.
Publicado: (1999)

Immune Responses in Pregnant Sows Induced by Recombinant Lactobacillus johnsonii Expressing the COE Protein of Porcine Epidemic Diarrhea Virus Provide Protection for Piglets against PEDV Infection
por: Zheng, Dianzhong, et al.
Publicado: (2021)

Genomic Characterizations of Porcine Epidemic Diarrhea Viruses (PEDV) in Diarrheic Piglets and Clinically Healthy Adult Pigs from 2019 to 2022 in China
por: Feng, Binghui, et al.
Publicado: (2023)

Growth enhancement of porcine epidemic diarrhea virus (PEDV) in Vero E6 cells expressing PEDV nucleocapsid protein
por: Liwnaree, Benjamas, et al.
Publicado: (2019)

Wild boars harboring porcine epidemic diarrhea virus (PEDV) may play an important role as a PEDV reservoir
por: Lee, Dong Uk, et al.
Publicado: (2016)

Deletion of both the Tyrosine-Based Endocytosis Signal and the Endoplasmic Reticulum Retrieval Signal in the Cytoplasmic Tail of Spike Protein Attenuates Porcine Epidemic Diarrhea Virus in Pigs
por: Hou, Yixuan, et al.
Publicado: (2019)

Evaluation of humoral immune status in porcine epidemic diarrhea virus (PEDV) infected sows under field conditions
por: Ouyang, Kang, et al.
Publicado: (2015)

Effectiveness of composting as a biosecure disposal method for porcine epidemic diarrhea virus (PEDV)-infected pig carcasses
por: Vitosh-Sillman, Sarah, et al.
Publicado: (2017)

Evidence of porcine epidemic diarrhea virus (PEDV) shedding in semen from infected specific pathogen-free boars
por: Gallien, Sarah, et al.
Publicado: (2018)

Porcine Epidemic Diarrhea Virus (PEDV) ORF3 Enhances Viral Proliferation by Inhibiting Apoptosis of Infected Cells
por: Si, Fusheng, et al.
Publicado: (2020)

Comparative Characterization and Pathogenicity of a Novel Porcine Epidemic Diarrhea Virus (PEDV) with a Naturally Occurring Truncated ORF3 Gene Coinfected with PEDVs Possessing an Intact ORF3 Gene in Piglets
por: Lu, Ying, et al.
Publicado: (2021)

Identification of a peptide derived from the heptad repeat 2 region of the porcine epidemic diarrhea virus (PEDV) spike glycoprotein that is capable of suppressing PEDV entry and inducing neutralizing antibodies
por: Zhao, Pengwei, et al.
Publicado: (2018)

Phylogeographic investigation of 2014 porcine epidemic diarrhea virus (PEDV) transmission in Taiwan
por: Sung, Ming-Hua, et al.
Publicado: (2019)

Phylogenetic tracking of current porcine epidemic diarrhea virus (PEDV) strains in the Philippines
por: Paraguison-Alili, Rubigilda, et al.
Publicado: (2016)

Diagnostic evaluation of assays for detection of antibodies against porcine epidemic diarrhea virus (PEDV) in pigs exposed to different PEDV strains
por: Gerber, Priscilla F., et al.
Publicado: (2016)

Differences in the intestinal microbiota between uninfected piglets and piglets infected with porcine epidemic diarrhea virus
por: Huang, Mei-Zhou, et al.
Publicado: (2018)

New variants of porcine epidemic diarrhea virus with large deletions in the spike protein, identified in the United States, 2016-2017
por: Su, Yunfang, et al.
Publicado: (2018)

Recombinant Chimeric Transmissible Gastroenteritis Virus (TGEV)—Porcine Epidemic Diarrhea Virus (PEDV) Virus Provides Protection against Virulent PEDV
por: Pascual-Iglesias, Alejandro, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_srvdm7n2s93hci4b6o3dfjb38t