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Mitral Subvalvular Aneurysm in a Patient with Chagas Disease and Recurrent Episodes of Ventricular Tachycardia

Subvalvular left ventricular aneurysm is a rare disease of obscure origin suggesting unique causes such as congenital, traumatic, and inflammatory or infectious diseases. Its mortality is closely related to heart failure, mitral insufficiency, thromboembolic phenomena, and cardiac arrhythmias. Altho...

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Autores principales: Grillo, Tereza Augusta, Athayde, Guilherme Rafael S., Belfort, Ana Flávia L., Miranda, Reynaldo C., Beaton, Andrea Z., Nascimento, Bruno R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655023/
https://www.ncbi.nlm.nih.gov/pubmed/26634158
http://dx.doi.org/10.1155/2015/213104
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author Grillo, Tereza Augusta
Athayde, Guilherme Rafael S.
Belfort, Ana Flávia L.
Miranda, Reynaldo C.
Beaton, Andrea Z.
Nascimento, Bruno R.
author_facet Grillo, Tereza Augusta
Athayde, Guilherme Rafael S.
Belfort, Ana Flávia L.
Miranda, Reynaldo C.
Beaton, Andrea Z.
Nascimento, Bruno R.
author_sort Grillo, Tereza Augusta
collection PubMed
description Subvalvular left ventricular aneurysm is a rare disease of obscure origin suggesting unique causes such as congenital, traumatic, and inflammatory or infectious diseases. Its mortality is closely related to heart failure, mitral insufficiency, thromboembolic phenomena, and cardiac arrhythmias. Although association with coronary artery disease is not described, the compression of epicardial vessels by the aneurysm may lead to ischemic manifestations. We report here a case of mitral subvalvular left ventricular aneurysm of probable chagasic origin, in a patient with normal left ventricular function evolving with repeated episodes of monomorphic ventricular tachycardia, despite noninducible electrophysiological testing and the use of optimal medical treatment, including amiodarone. The indication for implantable cardioverter-defibrillator in patients with Chagas cardiomyopathy and segmental wall motion abnormalities but without global systolic dysfunction remains unclear in literature, even in the presence of complex ventricular arrhythmias. A brief review of the literature on morphological features, diagnosis, prognosis, and treatment will be also discussed.
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spelling pubmed-46550232015-12-02 Mitral Subvalvular Aneurysm in a Patient with Chagas Disease and Recurrent Episodes of Ventricular Tachycardia Grillo, Tereza Augusta Athayde, Guilherme Rafael S. Belfort, Ana Flávia L. Miranda, Reynaldo C. Beaton, Andrea Z. Nascimento, Bruno R. Case Rep Cardiol Case Report Subvalvular left ventricular aneurysm is a rare disease of obscure origin suggesting unique causes such as congenital, traumatic, and inflammatory or infectious diseases. Its mortality is closely related to heart failure, mitral insufficiency, thromboembolic phenomena, and cardiac arrhythmias. Although association with coronary artery disease is not described, the compression of epicardial vessels by the aneurysm may lead to ischemic manifestations. We report here a case of mitral subvalvular left ventricular aneurysm of probable chagasic origin, in a patient with normal left ventricular function evolving with repeated episodes of monomorphic ventricular tachycardia, despite noninducible electrophysiological testing and the use of optimal medical treatment, including amiodarone. The indication for implantable cardioverter-defibrillator in patients with Chagas cardiomyopathy and segmental wall motion abnormalities but without global systolic dysfunction remains unclear in literature, even in the presence of complex ventricular arrhythmias. A brief review of the literature on morphological features, diagnosis, prognosis, and treatment will be also discussed. Hindawi Publishing Corporation 2015 2015-11-08 /pmc/articles/PMC4655023/ /pubmed/26634158 http://dx.doi.org/10.1155/2015/213104 Text en Copyright © 2015 Tereza Augusta Grillo et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report
Grillo, Tereza Augusta
Athayde, Guilherme Rafael S.
Belfort, Ana Flávia L.
Miranda, Reynaldo C.
Beaton, Andrea Z.
Nascimento, Bruno R.
Mitral Subvalvular Aneurysm in a Patient with Chagas Disease and Recurrent Episodes of Ventricular Tachycardia
title Mitral Subvalvular Aneurysm in a Patient with Chagas Disease and Recurrent Episodes of Ventricular Tachycardia
title_full Mitral Subvalvular Aneurysm in a Patient with Chagas Disease and Recurrent Episodes of Ventricular Tachycardia
title_fullStr Mitral Subvalvular Aneurysm in a Patient with Chagas Disease and Recurrent Episodes of Ventricular Tachycardia
title_full_unstemmed Mitral Subvalvular Aneurysm in a Patient with Chagas Disease and Recurrent Episodes of Ventricular Tachycardia
title_short Mitral Subvalvular Aneurysm in a Patient with Chagas Disease and Recurrent Episodes of Ventricular Tachycardia
title_sort mitral subvalvular aneurysm in a patient with chagas disease and recurrent episodes of ventricular tachycardia
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655023/
https://www.ncbi.nlm.nih.gov/pubmed/26634158
http://dx.doi.org/10.1155/2015/213104
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