Intrauterine Treatment of a Fetus with Familial Hypertrophic Cardiomyopathy Secondary to MYH7 Mutation

There is no clear consensus on optimal management of fetuses affected by familial hypertrophic cardiomyopathy (HCM). Intrauterine treatment of the condition has not been attempted in any standardized fashion. We report the case of a fetus treated by maternal propranolol during the third trimester af...

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Autores principales: Hill, Meghan G., Sekhon, Mehtab K., Reed, Kathryn L., Anderson, Caroline F., Borjon, Nydia D., Tardiff, Jil C., Barber, Brent J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2015
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655206/
https://www.ncbi.nlm.nih.gov/pubmed/26337809
http://dx.doi.org/10.1007/s00246-015-1250-1
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author Hill, Meghan G.
Sekhon, Mehtab K.
Reed, Kathryn L.
Anderson, Caroline F.
Borjon, Nydia D.
Tardiff, Jil C.
Barber, Brent J.
author_facet Hill, Meghan G.
Sekhon, Mehtab K.
Reed, Kathryn L.
Anderson, Caroline F.
Borjon, Nydia D.
Tardiff, Jil C.
Barber, Brent J.
author_sort Hill, Meghan G.
collection PubMed
description There is no clear consensus on optimal management of fetuses affected by familial hypertrophic cardiomyopathy (HCM). Intrauterine treatment of the condition has not been attempted in any standardized fashion. We report the case of a fetus treated by maternal propranolol during the third trimester after septal hypertrophy and diastolic dysfunction was diagnosed on fetal echocardiogram. The pregnancy went successfully to term, and fetal septal hypertrophy was noted to improve prior to delivery.
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spelling pubmed-46552062015-11-30 Intrauterine Treatment of a Fetus with Familial Hypertrophic Cardiomyopathy Secondary to MYH7 Mutation Hill, Meghan G. Sekhon, Mehtab K. Reed, Kathryn L. Anderson, Caroline F. Borjon, Nydia D. Tardiff, Jil C. Barber, Brent J. Pediatr Cardiol Case Report There is no clear consensus on optimal management of fetuses affected by familial hypertrophic cardiomyopathy (HCM). Intrauterine treatment of the condition has not been attempted in any standardized fashion. We report the case of a fetus treated by maternal propranolol during the third trimester after septal hypertrophy and diastolic dysfunction was diagnosed on fetal echocardiogram. The pregnancy went successfully to term, and fetal septal hypertrophy was noted to improve prior to delivery. Springer US 2015-09-04 2015 /pmc/articles/PMC4655206/ /pubmed/26337809 http://dx.doi.org/10.1007/s00246-015-1250-1 Text en © The Author(s) 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
spellingShingle Case Report
Hill, Meghan G.
Sekhon, Mehtab K.
Reed, Kathryn L.
Anderson, Caroline F.
Borjon, Nydia D.
Tardiff, Jil C.
Barber, Brent J.
Intrauterine Treatment of a Fetus with Familial Hypertrophic Cardiomyopathy Secondary to MYH7 Mutation
title Intrauterine Treatment of a Fetus with Familial Hypertrophic Cardiomyopathy Secondary to MYH7 Mutation
title_full Intrauterine Treatment of a Fetus with Familial Hypertrophic Cardiomyopathy Secondary to MYH7 Mutation
title_fullStr Intrauterine Treatment of a Fetus with Familial Hypertrophic Cardiomyopathy Secondary to MYH7 Mutation
title_full_unstemmed Intrauterine Treatment of a Fetus with Familial Hypertrophic Cardiomyopathy Secondary to MYH7 Mutation
title_short Intrauterine Treatment of a Fetus with Familial Hypertrophic Cardiomyopathy Secondary to MYH7 Mutation
title_sort intrauterine treatment of a fetus with familial hypertrophic cardiomyopathy secondary to myh7 mutation
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655206/
https://www.ncbi.nlm.nih.gov/pubmed/26337809
http://dx.doi.org/10.1007/s00246-015-1250-1
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