Cargando…

Metformin and Ara-a Effectively Suppress Brain Cancer by Targeting Cancer Stem/Progenitor Cells

Background: Gliomas and neuroblastomas pose a great health burden worldwide with a poor and moderate prognosis, respectively. Many studies have tried to find effective treatments for these primary malignant brain tumors. Of interest, the AMP-activated protein kinase (AMPK) pathway was found to be as...

Descripción completa

Detalles Bibliográficos
Autores principales:	Mouhieddine, Tarek H., Nokkari, Amaly, Itani, Muhieddine M., Chamaa, Farah, Bahmad, Hisham, Monzer, Alissar, El-Merahbi, Rabih, Daoud, Georges, Eid, Assaad, Kobeissy, Firas H., Abou-Kheir, Wassim
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655242/ https://www.ncbi.nlm.nih.gov/pubmed/26635517 http://dx.doi.org/10.3389/fnins.2015.00442

Ejemplares similares

The Akt/mTOR pathway in cancer stem/progenitor cells is a potential therapeutic target for glioblastoma and neuroblastoma
por: Bahmad, Hisham F., et al.
Publicado: (2018)

Primary versus castration-resistant prostate cancer: modeling through novel murine prostate cancer cell lines
por: Daoud, Georges, et al.
Publicado: (2016)

Stem cells in neuroinjury and neurodegenerative disorders: challenges and future neurotherapeutic prospects
por: Mouhieddine, Tarek H., et al.
Publicado: (2014)

Berberis libanotica Ehrenb Extract Shows Anti-Neoplastic Effects on Prostate Cancer Stem/Progenitor Cells
por: El-Merahbi, Rabih, et al.
Publicado: (2014)

Characterization of the Kallikrein-Kinin System Post Chemical Neuronal Injury: An In Vitro Biochemical and Neuroproteomics Assessment
por: Nokkari, Amaly, et al.
Publicado: (2015)

Correction: Characterization of the Kallikrein-Kinin System Post Chemical Neuronal Injury: An In Vitro Biochemical and Neuroproteomics Assessment
por: Nokkari, Amaly, et al.
Publicado: (2015)

Protein Expression Analysis of an In Vitro Murine Model of Prostate Cancer Progression: Towards Identification of High-Potential Therapeutic Targets
por: Bahmad, Hisham F., et al.
Publicado: (2020)

A Unique Expression of Keratin 14 in a Subset of Trophoblast Cells
por: Abou-Kheir, Wassim, et al.
Publicado: (2015)

Genome-wide gene expression analysis of a murine model of prostate cancer progression: Deciphering the roles of IL-6 and p38 MAPK as potential therapeutic targets
por: Daouk, Reem, et al.
Publicado: (2020)

The Effect of Chronic Methamphetamine Exposure on the Hippocampal and Olfactory Bulb Neuroproteomes of Rats
por: Zhu, Rui, et al.
Publicado: (2016)

Cancer Stem Cells in Neuroblastoma: Expanding the Therapeutic Frontier
por: Bahmad, Hisham F., et al.
Publicado: (2019)

Sphere-Formation Assay: Three-Dimensional in vitro Culturing of Prostate Cancer Stem/Progenitor Sphere-Forming Cells
por: Bahmad, Hisham F., et al.
Publicado: (2018)

Modeling Human Neurological and Neurodegenerative Diseases: From Induced Pluripotent Stem Cells to Neuronal Differentiation and Its Applications in Neurotrauma
por: Bahmad, Hisham, et al.
Publicado: (2017)

The Use of Stem Cell-Derived Organoids in Disease Modeling: An Update
por: Azar, Joseph, et al.
Publicado: (2021)

Crosstalk between COVID-19 and prostate cancer
por: Bahmad, Hisham F., et al.
Publicado: (2020)

Nitrous Oxide Induces Prominent Cell Proliferation in Adult Rat Hippocampal Dentate Gyrus
por: Chamaa, Farah, et al.
Publicado: (2018)

Prostate Cancer and Aspirin Use: Synopsis of the Proposed Molecular Mechanisms
por: Bilani, Nadeem, et al.
Publicado: (2017)

Cancerona: Challenges of Cancer Management in Times of COVID-19 Pandemic
por: Ballout, Farah, et al.
Publicado: (2020)

PTSD in the COVID-19 Era
por: Chamaa, Farah, et al.
Publicado: (2021)

Establishment and characterization of prostate organoids from treatment-naïve patients with prostate cancer
por: Cheaito, Katia, et al.
Publicado: (2022)

Colorectal and Prostate Cancer Risk in Diabetes: Metformin, an Actor behind the Scene
por: Anwar, M. Akhtar, et al.
Publicado: (2014)

Systems Biology, Bioinformatics, and Biomarkers in Neuropsychiatry
por: Alawieh, Ali, et al.
Publicado: (2012)

Thymoquinone induces apoptosis and DNA damage in 5-Fluorouracil-resistant colorectal cancer stem/progenitor cells
por: Ballout, Farah, et al.
Publicado: (2020)

Intranigral Injection of Endotoxin Suppresses Proliferation of Hippocampal Progenitor Cells
por: Darwish, Batoul, et al.
Publicado: (2019)

Genomic alterations during p53-dependent apoptosis induced by γ-irradiation of Molt-4 leukemia cells
por: Hage-Sleiman, Rouba, et al.
Publicado: (2017)

Urinary Tract Infections Impair Adult Hippocampal Neurogenesis
por: Darwish, Batoul, et al.
Publicado: (2022)

Assessing Radiosensitivity of Bladder Cancer in vitro: A 2D vs. 3D Approach
por: Bodgi, Larry, et al.
Publicado: (2019)

Epithelial-to-Mesenchymal Transition-Related Markers in Prostate Cancer: From Bench to Bedside
por: Gogola, Samantha, et al.
Publicado: (2023)

Thymoquinone Radiosensitizes Human Colorectal Cancer Cells in 2D and 3D Culture Models
por: Al Bitar, Samar, et al.
Publicado: (2022)

Chemosensitivity of U251 Cells to the Co-treatment of D-Penicillamine and Copper: Possible Implications on Wilson Disease Patients
por: Katerji, Meghri, et al.
Publicado: (2017)

Sustained Activation of the Anterior Thalamic Neurons with Low Doses of Kainic Acid Boosts Hippocampal Neurogenesis
por: Chamaa, Farah, et al.
Publicado: (2022)

Genome-Wide and Phenotypic Evaluation of Stem Cell Progenitors Derived From Gprc5a-Deficient Murine Lung Adenocarcinoma With Somatic Kras Mutations
por: Daouk, Reem, et al.
Publicado: (2019)

Central nervous system tumors and three-dimensional cell biology: Current and future perspectives in modeling
por: Abou-Mrad, Zaki, et al.
Publicado: (2021)

Novel therapeutic diiminoquinone exhibits anticancer effects on human colorectal cancer cells in two-dimensional and three-dimensional in vitro models
por: Monzer, Alissar, et al.
Publicado: (2022)

Modeling Adipogenesis: Current and Future Perspective
por: Bahmad, Hisham F., et al.
Publicado: (2020)

Triple‐marker immunohistochemical assessment of muscle‐invasive bladder cancer: Is there prognostic significance?
por: Labban, Muhieddine, et al.
Publicado: (2021)

Tumor Microenvironment in Prostate Cancer: Toward Identification of Novel Molecular Biomarkers for Diagnosis, Prognosis, and Therapy Development
por: Bahmad, Hisham F., et al.
Publicado: (2021)

Epidermal Growth Factor Is Essential for the Maintenance of Novel Prostate Epithelial Cells Isolated From Patient-Derived Organoids
por: Cheaito, Katia, et al.
Publicado: (2020)

Novel Bioinformatics–Based Approach for Proteomic Biomarkers Prediction of Calpain-2 & Caspase-3 Protease Fragmentation: Application to βII-Spectrin Protein
por: El-Assaad, Atlal, et al.
Publicado: (2017)

Ara solar
por: Anguiano Valadez, Adolfo, 1917-
Publicado: (1974)

Cannot write session to /tmp/vufind_sessions/sess_1ts6e5fcjg4k2bfpf5uivj5hvc