Cargando…
Computational Modelling Approaches on Epigenetic Factors in Neurodegenerative and Autoimmune Diseases and Their Mechanistic Analysis
Neurodegenerative as well as autoimmune diseases have unclear aetiologies, but an increasing number of evidences report for a combination of genetic and epigenetic alterations that predispose for the development of disease. This review examines the major milestones in epigenetics research in the con...
Autores principales: | Khanam Irin, Afroza, Tom Kodamullil, Alpha, Gündel, Michaela, Hofmann-Apitius, Martin |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi Publishing Corporation
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655260/ https://www.ncbi.nlm.nih.gov/pubmed/26636108 http://dx.doi.org/10.1155/2015/737168 |
Ejemplares similares
-
Using Drugs as Molecular Probes: A Computational Chemical Biology Approach in Neurodegenerative Diseases
por: Emon, Mohammad Asif Emran Khan, et al.
Publicado: (2017) -
Reasoning over genetic variance information in cause-and-effect models of neurodegenerative diseases
por: Naz, Mufassra, et al.
Publicado: (2016) -
Quantifying mechanisms in neurodegenerative diseases (NDDs) using candidate mechanism perturbation amplitude (CMPA) algorithm
por: Karki, Reagon, et al.
Publicado: (2019) -
Multimodal mechanistic signatures for neurodegenerative diseases (NeuroMMSig): a web server for mechanism enrichment
por: Domingo-Fernández, Daniel, et al.
Publicado: (2017) -
NeuroTransDB: highly curated and structured transcriptomic metadata for neurodegenerative diseases
por: Bagewadi, Shweta, et al.
Publicado: (2015)