Constitutive Activation of the Nlrc4 Inflammasome Prevents Hepatic Fibrosis and Promotes Hepatic Regeneration after Partial Hepatectomy

TThe molecular mechanisms responsible for the development of hepatic fibrosis are not fully understood. The Nlrc4 inflammasome detects cytosolic presence of bacterial components, activating inflammatory cytokines to facilitate clearance of pathogens and infected cells. We hypothesized that low-grade...

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Detalles Bibliográficos
Autores principales: DeSantis, David A., Ko, Chih-Wei, Wang, Lan, Lee, Peter, Croniger, Colleen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655266/
https://www.ncbi.nlm.nih.gov/pubmed/26635450
http://dx.doi.org/10.1155/2015/909827

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