CUL4A facilitates hepatocarcinogenesis by promoting cell cycle progression and epithelial-mesenchymal transition

CUL4A, a member of the CULLIN family, functions as a scaffold protein for an E3 ubiquitin ligase. It was reported that the CUL4A gene showed amplification in some human primary hepatocellular carcinomas (HCC). However, the exact role of CUL4A in HCC remains unknown. Here, we aimed to investigate the...

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Detalles Bibliográficos
Autores principales: Pan, Yingfang, Wang, Bo, Yang, Xiaoyun, Bai, Fuxiang, Xu, Qun, Li, Xueen, Gao, Lifen, Ma, Chunhong, Liang, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655319/
https://www.ncbi.nlm.nih.gov/pubmed/26593394
http://dx.doi.org/10.1038/srep17006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655319/
https://www.ncbi.nlm.nih.gov/pubmed/26593394
http://dx.doi.org/10.1038/srep17006

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