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CUL4A facilitates hepatocarcinogenesis by promoting cell cycle progression and epithelial-mesenchymal transition
CUL4A, a member of the CULLIN family, functions as a scaffold protein for an E3 ubiquitin ligase. It was reported that the CUL4A gene showed amplification in some human primary hepatocellular carcinomas (HCC). However, the exact role of CUL4A in HCC remains unknown. Here, we aimed to investigate the...
Autores principales: | Pan, Yingfang, Wang, Bo, Yang, Xiaoyun, Bai, Fuxiang, Xu, Qun, Li, Xueen, Gao, Lifen, Ma, Chunhong, Liang, Xiaohong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655319/ https://www.ncbi.nlm.nih.gov/pubmed/26593394 http://dx.doi.org/10.1038/srep17006 |
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