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Identification of novel, therapy-responsive protein biomarkers in a mouse model of Duchenne muscular dystrophy by aptamer-based serum proteomics
There is currently an urgent need for biomarkers that can be used to monitor the efficacy of experimental therapies for Duchenne Muscular Dystrophy (DMD) in clinical trials. Identification of novel protein biomarkers has been limited due to the massive complexity of the serum proteome and the presen...
Autores principales: | Coenen-Stass, Anna M. L., McClorey, Graham, Manzano, Raquel, Betts, Corinne A., Blain, Alison, Saleh, Amer F., Gait, Michael J., Lochmüller, Hanns, Wood, Matthew J. A., Roberts, Thomas C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655324/ https://www.ncbi.nlm.nih.gov/pubmed/26594036 http://dx.doi.org/10.1038/srep17014 |
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