Structural Relationship of the Lipid A Acyl Groups to Activation of Murine Toll-Like Receptor 4 by Lipopolysaccharides from Pathogenic Strains of Burkholderia mallei, Acinetobacter baumannii, and Pseudomonas aeruginosa

Toll-like receptor 4 (TLR4) is required for activation of innate immunity upon recognition of lipopolysaccharide (LPS) of Gram-negative bacteria. The ability of TLR4 to respond to a particular LPS species is important since insufficient activation may not prevent bacterial growth while excessive imm...

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Detalles Bibliográficos
Autores principales: Korneev, Kirill V., Arbatsky, Nikolay P., Molinaro, Antonio, Palmigiano, Angelo, Shaikhutdinova, Rima Z., Shneider, Mikhail M., Pier, Gerald B., Kondakova, Anna N., Sviriaeva, Ekaterina N., Sturiale, Luisa, Garozzo, Domenico, Kruglov, Andrey A., Nedospasov, Sergei A., Drutskaya, Marina S., Knirel, Yuriy A., Kuprash, Dmitry V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655328/
https://www.ncbi.nlm.nih.gov/pubmed/26635809
http://dx.doi.org/10.3389/fimmu.2015.00595

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