P2×7 purinergic signaling in dilated cardiomyopathy induced by auto-immunity against muscarinic M(2) receptors: autoantibody levels, heart functionality and cytokine expression

Autoantibodies against the M(2) receptors (M(2)AChR) have been associated with Dilated Cardiomyopathy (DCM). In the heart, P2×7 receptors influence electrical conduction, coronary circulation and response to ischemia. They can also trigger pro-inflammatory responses and the development of neurologic...

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Detalles Bibliográficos
Autores principales: Martinez, Camila Guerra, Zamith-Miranda, Daniel, da Silva, Marcia Gracindo, Ribeiro, Karla Consort, Brandão, Izaíra Trincani, Silva, Celio Lopes, Diaz, Bruno Lourenço, Bellio, Maria, Persechini, Pedro Muanis, Kurtenbach, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655336/
https://www.ncbi.nlm.nih.gov/pubmed/26592184
http://dx.doi.org/10.1038/srep16940

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