Expanding the scope of Metal-Free enantioselective allylic substitutions: Anthrones

The highly enantioselective asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates with anthrones is presented. The reaction is simply catalyzed by cinchona alkaloid derivatives affording the final alkylated products in good yields and excellent enantioselectivities.

Detalles Bibliográficos
Autores principales: Ceban, Victor, Tauchman, Jiří, Meazza, Marta, Gallagher, Greg, Light, Mark E., Gergelitsová, Ivana, Veselý, Jan, Rios, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655356/
https://www.ncbi.nlm.nih.gov/pubmed/26592555
http://dx.doi.org/10.1038/srep16886
Descripción
Sumario:The highly enantioselective asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates with anthrones is presented. The reaction is simply catalyzed by cinchona alkaloid derivatives affording the final alkylated products in good yields and excellent enantioselectivities.

Ejemplares similares