Expanding the scope of Metal-Free enantioselective allylic substitutions: Anthrones

The highly enantioselective asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates with anthrones is presented. The reaction is simply catalyzed by cinchona alkaloid derivatives affording the final alkylated products in good yields and excellent enantioselectivities.

Detalles Bibliográficos
Autores principales: Ceban, Victor, Tauchman, Jiří, Meazza, Marta, Gallagher, Greg, Light, Mark E., Gergelitsová, Ivana, Veselý, Jan, Rios, Ramon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2015
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655356/
https://www.ncbi.nlm.nih.gov/pubmed/26592555
http://dx.doi.org/10.1038/srep16886
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author Ceban, Victor
Tauchman, Jiří
Meazza, Marta
Gallagher, Greg
Light, Mark E.
Gergelitsová, Ivana
Veselý, Jan
Rios, Ramon
author_facet Ceban, Victor
Tauchman, Jiří
Meazza, Marta
Gallagher, Greg
Light, Mark E.
Gergelitsová, Ivana
Veselý, Jan
Rios, Ramon
author_sort Ceban, Victor
collection PubMed
description The highly enantioselective asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates with anthrones is presented. The reaction is simply catalyzed by cinchona alkaloid derivatives affording the final alkylated products in good yields and excellent enantioselectivities.
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spelling pubmed-46553562015-11-27 Expanding the scope of Metal-Free enantioselective allylic substitutions: Anthrones Ceban, Victor Tauchman, Jiří Meazza, Marta Gallagher, Greg Light, Mark E. Gergelitsová, Ivana Veselý, Jan Rios, Ramon Sci Rep Article The highly enantioselective asymmetric allylic alkylation of Morita–Baylis–Hillman carbonates with anthrones is presented. The reaction is simply catalyzed by cinchona alkaloid derivatives affording the final alkylated products in good yields and excellent enantioselectivities. Nature Publishing Group 2015-11-23 /pmc/articles/PMC4655356/ /pubmed/26592555 http://dx.doi.org/10.1038/srep16886 Text en Copyright © 2015, Macmillan Publishers Limited http://creativecommons.org/licenses/by/4.0/ This work is licensed under a Creative Commons Attribution 4.0 International License. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in the credit line; if the material is not included under the Creative Commons license, users will need to obtain permission from the license holder to reproduce the material. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/
spellingShingle Article
Ceban, Victor
Tauchman, Jiří
Meazza, Marta
Gallagher, Greg
Light, Mark E.
Gergelitsová, Ivana
Veselý, Jan
Rios, Ramon
Expanding the scope of Metal-Free enantioselective allylic substitutions: Anthrones
title Expanding the scope of Metal-Free enantioselective allylic substitutions: Anthrones
title_full Expanding the scope of Metal-Free enantioselective allylic substitutions: Anthrones
title_fullStr Expanding the scope of Metal-Free enantioselective allylic substitutions: Anthrones
title_full_unstemmed Expanding the scope of Metal-Free enantioselective allylic substitutions: Anthrones
title_short Expanding the scope of Metal-Free enantioselective allylic substitutions: Anthrones
title_sort expanding the scope of metal-free enantioselective allylic substitutions: anthrones
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655356/
https://www.ncbi.nlm.nih.gov/pubmed/26592555
http://dx.doi.org/10.1038/srep16886
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