Cross-talk between bone morphogenetic proteins and inflammatory pathways

Pro-inflammatory cytokines and bone morphogenetic proteins are generally studied separately and considered to be elements of different worlds, immunology and developmental biology. Varas and colleagues report that these factors show cross-talk in rheumatoid arthritis synoviocytes. They show that pro...

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Detalles Bibliográficos
Autores principales: van der Kraan, Peter M., Davidson, Esmeralda N. Blaney
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Editorial
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655495/
https://www.ncbi.nlm.nih.gov/pubmed/26592526
http://dx.doi.org/10.1186/s13075-015-0817-9
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author van der Kraan, Peter M.
Davidson, Esmeralda N. Blaney
author_facet van der Kraan, Peter M.
Davidson, Esmeralda N. Blaney
author_sort van der Kraan, Peter M.
collection PubMed
description Pro-inflammatory cytokines and bone morphogenetic proteins are generally studied separately and considered to be elements of different worlds, immunology and developmental biology. Varas and colleagues report that these factors show cross-talk in rheumatoid arthritis synoviocytes. They show that pro-inflammatory cytokines not only stimulate the production of bone morphogenetic proteins but that these endogenously produced bone morphogenetic proteins interfere with the effects of pro-inflammatory cytokines on synoviocytes.
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spelling pubmed-46554952015-11-24 Cross-talk between bone morphogenetic proteins and inflammatory pathways van der Kraan, Peter M. Davidson, Esmeralda N. Blaney Arthritis Res Ther Editorial Pro-inflammatory cytokines and bone morphogenetic proteins are generally studied separately and considered to be elements of different worlds, immunology and developmental biology. Varas and colleagues report that these factors show cross-talk in rheumatoid arthritis synoviocytes. They show that pro-inflammatory cytokines not only stimulate the production of bone morphogenetic proteins but that these endogenously produced bone morphogenetic proteins interfere with the effects of pro-inflammatory cytokines on synoviocytes. BioMed Central 2015-11-23 2015 /pmc/articles/PMC4655495/ /pubmed/26592526 http://dx.doi.org/10.1186/s13075-015-0817-9 Text en © van der Kraan and Davidson. 2015 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Editorial
van der Kraan, Peter M.
Davidson, Esmeralda N. Blaney
Cross-talk between bone morphogenetic proteins and inflammatory pathways
title Cross-talk between bone morphogenetic proteins and inflammatory pathways
title_full Cross-talk between bone morphogenetic proteins and inflammatory pathways
title_fullStr Cross-talk between bone morphogenetic proteins and inflammatory pathways
title_full_unstemmed Cross-talk between bone morphogenetic proteins and inflammatory pathways
title_short Cross-talk between bone morphogenetic proteins and inflammatory pathways
title_sort cross-talk between bone morphogenetic proteins and inflammatory pathways
topic Editorial
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655495/
https://www.ncbi.nlm.nih.gov/pubmed/26592526
http://dx.doi.org/10.1186/s13075-015-0817-9
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