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Heterozygous Deletion of α-Neurexin I or α-Neurexin II Results in Behaviors Relevant to Autism and Schizophrenia
The neurexins are a family of presynaptic cell adhesion molecules. Human genetic studies have found heterozygous deletions affecting NRXN1 and NRXN2, encoding α-neurexin I (Nrxn1α) and α-neurexin II (Nrxn2α), in individuals with autism spectrum disorders and schizophrenia. However, the link between...
Autores principales: | Dachtler, James, Ivorra, Jose L., Rowland, Tessa E., Lever, Colin, Rodgers, R. John, Clapcote, Steven J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Psychological Association
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655861/ https://www.ncbi.nlm.nih.gov/pubmed/26595880 http://dx.doi.org/10.1037/bne0000108 |
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