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A quantitative assay to monitor HSV-1 ICP0 ubiquitin ligase activity in vitro
The ubiquitin–proteasome system is an essential cellular process that plays a fundamental role in the regulation of protein stability. This pathway is tightly controlled by a sequential cascade of enzymatic steps that culminates in the formation of a poly-ubiquitin chain onto the substrate protein t...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Academic Press
2015
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655872/ https://www.ncbi.nlm.nih.gov/pubmed/25862948 http://dx.doi.org/10.1016/j.ymeth.2015.04.004 |