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Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension

Computed tomography (CT) is widely used for evaluation of lung diseases. To evaluate the value of CT measurement of pulmonary artery for diagnosis of chronic obstructive pulmonary disease (COPD) and its comorbidity pulmonary hypertension (PH), we retrospectively reviewed the CT of 221 patients with...

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Autores principales: Chen, Xuesong, Liu, Kouying, Wang, Zhiyue, Zhu, Yinsu, Zhao, Yang, Kong, Hui, Xie, Weiping, Wang, Hong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655902/
https://www.ncbi.nlm.nih.gov/pubmed/26604739
http://dx.doi.org/10.2147/COPD.S94211
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author Chen, Xuesong
Liu, Kouying
Wang, Zhiyue
Zhu, Yinsu
Zhao, Yang
Kong, Hui
Xie, Weiping
Wang, Hong
author_facet Chen, Xuesong
Liu, Kouying
Wang, Zhiyue
Zhu, Yinsu
Zhao, Yang
Kong, Hui
Xie, Weiping
Wang, Hong
author_sort Chen, Xuesong
collection PubMed
description Computed tomography (CT) is widely used for evaluation of lung diseases. To evaluate the value of CT measurement of pulmonary artery for diagnosis of chronic obstructive pulmonary disease (COPD) and its comorbidity pulmonary hypertension (PH), we retrospectively reviewed the CT of 221 patients with COPD and 115 control patients without cardiovascular or lung disease. Patients with COPD were divided into PH (COPD-PH) and non-PH according to systolic pulmonary artery pressure. Main pulmonary artery (MPA), right pulmonary artery (RPA) and left pulmonary artery branches, and ascending aorta (AAo) and descending aorta (DAo) diameters were measured. Meanwhile, the ratios of MPA/AAo and MPA/DAo were calculated. MPA, RPA, and left pulmonary artery diameters were significantly larger in COPD than those in the controls, and this augment was more obvious in COPD-PH. AAo and DAo diameters did not vary obviously between groups, while MPA/AAo and MAP/DAo increased significantly in COPD and PH. MPA could be helpful for COPD diagnosis (MPA diameter ≥27.5 mm, sensitivity 54%, and specificity 80%), and RPA could be applied for COPD-PH diagnosis (RPA diameter ≥23.4 mm, sensitivity 67%, and specificity 76%). There was a marked correlation between MPA/DAo and systolic pulmonary artery pressure (r=0.594, P<0.001). Therefore, chest CT could be a simple and effective modality for diagnostic evaluation of COPD and its comorbidity, PH.
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spelling pubmed-46559022015-11-24 Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension Chen, Xuesong Liu, Kouying Wang, Zhiyue Zhu, Yinsu Zhao, Yang Kong, Hui Xie, Weiping Wang, Hong Int J Chron Obstruct Pulmon Dis Original Research Computed tomography (CT) is widely used for evaluation of lung diseases. To evaluate the value of CT measurement of pulmonary artery for diagnosis of chronic obstructive pulmonary disease (COPD) and its comorbidity pulmonary hypertension (PH), we retrospectively reviewed the CT of 221 patients with COPD and 115 control patients without cardiovascular or lung disease. Patients with COPD were divided into PH (COPD-PH) and non-PH according to systolic pulmonary artery pressure. Main pulmonary artery (MPA), right pulmonary artery (RPA) and left pulmonary artery branches, and ascending aorta (AAo) and descending aorta (DAo) diameters were measured. Meanwhile, the ratios of MPA/AAo and MPA/DAo were calculated. MPA, RPA, and left pulmonary artery diameters were significantly larger in COPD than those in the controls, and this augment was more obvious in COPD-PH. AAo and DAo diameters did not vary obviously between groups, while MPA/AAo and MAP/DAo increased significantly in COPD and PH. MPA could be helpful for COPD diagnosis (MPA diameter ≥27.5 mm, sensitivity 54%, and specificity 80%), and RPA could be applied for COPD-PH diagnosis (RPA diameter ≥23.4 mm, sensitivity 67%, and specificity 76%). There was a marked correlation between MPA/DAo and systolic pulmonary artery pressure (r=0.594, P<0.001). Therefore, chest CT could be a simple and effective modality for diagnostic evaluation of COPD and its comorbidity, PH. Dove Medical Press 2015-11-18 /pmc/articles/PMC4655902/ /pubmed/26604739 http://dx.doi.org/10.2147/COPD.S94211 Text en © 2015 Chen et al. This work is published by Dove Medical Press Limited, and licensed under Creative Commons Attribution – Non Commercial (unported, v3.0) License The full terms of the License are available at http://creativecommons.org/licenses/by-nc/3.0/. Non-commercial uses of the work are permitted without any further permission from Dove Medical Press Limited, provided the work is properly attributed.
spellingShingle Original Research
Chen, Xuesong
Liu, Kouying
Wang, Zhiyue
Zhu, Yinsu
Zhao, Yang
Kong, Hui
Xie, Weiping
Wang, Hong
Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension
title Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension
title_full Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension
title_fullStr Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension
title_full_unstemmed Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension
title_short Computed tomography measurement of pulmonary artery for diagnosis of COPD and its comorbidity pulmonary hypertension
title_sort computed tomography measurement of pulmonary artery for diagnosis of copd and its comorbidity pulmonary hypertension
topic Original Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655902/
https://www.ncbi.nlm.nih.gov/pubmed/26604739
http://dx.doi.org/10.2147/COPD.S94211
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