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Combination of PEI-Mn(0.5)Zn(0.5)Fe(2)O(4) nanoparticles and pHsp 70-HSV-TK/GCV with magnet-induced heating for treatment of hepatoma
BACKGROUND: To explore a new combination of thermal treatment and gene therapy for hepatoma, a heat-inducible herpes simplex virus thymidine kinase/ganciclovir (HSV-TK/GCV) gene therapy system was developed in which thermal energy generated by Mn(0.5)Zn(0.5)Fe(2)O(4) nanoparticles (MZF-NPs) under an...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4655962/ https://www.ncbi.nlm.nih.gov/pubmed/26604760 http://dx.doi.org/10.2147/IJN.S92179 |