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A peep into mitochondrial disorder: multifaceted from mitochondrial DNA mutations to nuclear gene modulation
Mitochondrial genome is responsible for multiple human diseases in a maternal inherited pattern, yet phenotypes of patients in a same pedigree frequently vary largely. Genes involving in epigenetic modification, RNA processing, and other biological pathways, rather than “threshold effect” and enviro...
Autores principales: | Chen, Chao, Chen, Ye, Guan, Min-Xin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Higher Education Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656216/ https://www.ncbi.nlm.nih.gov/pubmed/26084519 http://dx.doi.org/10.1007/s13238-015-0175-z |
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