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RNA Sequencing of Tumor-Associated Microglia Reveals Ccl5 as a Stromal Chemokine Critical for Neurofibromatosis-1 Glioma Growth()
Solid cancers develop within a supportive microenvironment that promotes tumor formation and growth through the elaboration of mitogens and chemokines. Within these tumors, monocytes (macrophages and microglia) represent rich sources of these stromal factors. Leveraging a genetically engineered mous...
Autores principales: | Solga, Anne C., Pong, Winnie W., Kim, Keun-Young, Cimino, Patrick J., Toonen, Joseph A., Walker, Jason, Wylie, Todd, Magrini, Vincent, Griffith, Malachi, Griffith, Obi L., Ly, Amy, Ellisman, Mark H., Mardis, Elaine R., Gutmann, David H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Neoplasia Press
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656811/ https://www.ncbi.nlm.nih.gov/pubmed/26585233 http://dx.doi.org/10.1016/j.neo.2015.10.002 |
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