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Hippocampal Transcriptomic and Proteomic Alterations in the BTBR Mouse Model of Autism Spectrum Disorder

Autism spectrum disorders (ASD) are complex heterogeneous neurodevelopmental disorders of an unclear etiology, and no cure currently exists. Prior studies have demonstrated that the black and tan, brachyury (BTBR) T+ Itpr3tf/J mouse strain displays a behavioral phenotype with ASD-like features. BTBR...

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Detalles Bibliográficos
Autores principales: Daimon, Caitlin M., Jasien, Joan M., Wood, William H., Zhang, Yongqing, Becker, Kevin G., Silverman, Jill L., Crawley, Jacqueline N., Martin, Bronwen, Maudsley, Stuart
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656818/
https://www.ncbi.nlm.nih.gov/pubmed/26635614
http://dx.doi.org/10.3389/fphys.2015.00324