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Both Orai1 and TRPC1 are Involved in Excessive Store-Operated Calcium Entry in Striatal Neurons Expressing Mutant Huntingtin Exon 1

It has been previously reported that N-terminus of mutant huntingtin (product of the 1st exon) is sufficient to cause a Huntington's disease (HD) pathological phenotype. In view of recent data suggesting that improper regulation of store-operated calcium (SOC) channels is involved in neurodegen...

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Detalles Bibliográficos
Autores principales:	Vigont, Vladimir, Kolobkova, Yulia, Skopin, Anton, Zimina, Olga, Zenin, Valery, Glushankova, Lyuba, Kaznacheyeva, Elena
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2015
Materias:	Physiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656824/ https://www.ncbi.nlm.nih.gov/pubmed/26635623 http://dx.doi.org/10.3389/fphys.2015.00337

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