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Telomeres and Telomerase in the Radiation Response: Implications for Instability, Reprograming, and Carcinogenesis
Telomeres are nucleoprotein complexes comprised of tandem arrays of repetitive DNA sequence that serve to protect chromosomal termini from inappropriate degradation, as well as to prevent these natural DNA ends from being recognized as broken DNA (double-strand breaks) and triggering of inappropriat...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2015
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656829/ https://www.ncbi.nlm.nih.gov/pubmed/26636039 http://dx.doi.org/10.3389/fonc.2015.00257 |