Thrombin-induced reactive oxygen species generation in platelets: A novel role for protease-activated receptor 4 and GPIbα

BACKGROUND: Platelets are essential for maintaining haemostasis and play a key role in the pathogenesis of cardiovascular disease. Upon ligation of platelet receptors through subendothelial matrix proteins, intracellular reactive oxygen species (ROS) are generated, further amplifying the platelet ac...

Descripción completa

Detalles Bibliográficos
Autores principales: Carrim, Naadiya, Arthur, Jane F., Hamilton, Justin R., Gardiner, Elizabeth E., Andrews, Robert K., Moran, Niamh, Berndt, Michael C., Metharom, Pat
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2015
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656914/
https://www.ncbi.nlm.nih.gov/pubmed/26569550
http://dx.doi.org/10.1016/j.redox.2015.10.009

Ejemplares similares

Ejemplares similares