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Septic knee arthritis in Crohn’s disease biological therapy-free patient. Case report

A 52-year-old woman with Crohn’s disease presented with septic arthrtis of the knee. This condition coincided with a symptomatic flare of her Crohn’s disease due to an ileal inflammatory stenosis, manifested as a phlegmonous mass palpable in the right lower quadrant and a small bowel obstruction. Re...

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Detalles Bibliográficos
Autores principales: Pop, C, Calagiu, D, Jantea, P, Nemes, R
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Carol Davila University Press 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656959/
https://www.ncbi.nlm.nih.gov/pubmed/26664477
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author Pop, C
Calagiu, D
Jantea, P
Nemes, R
author_facet Pop, C
Calagiu, D
Jantea, P
Nemes, R
author_sort Pop, C
collection PubMed
description A 52-year-old woman with Crohn’s disease presented with septic arthrtis of the knee. This condition coincided with a symptomatic flare of her Crohn’s disease due to an ileal inflammatory stenosis, manifested as a phlegmonous mass palpable in the right lower quadrant and a small bowel obstruction. Results of synovial fluid cultures showed the presence of Gram-negative bacillus, Klebsiella pneumoniae and the CT scan images were highly suggestive of abdominal abscess within Crohn’s disease. The patient’s condition improved after following an antibiotic treatment and after the initiation of Anti-TNF-alpha agent Adalimumab, with no further exacerbation. Septic arthritis in Crohn’s disease should be considered to have a communicating source of sepsis consisting of an abdominal abscess or fistula. Abbreviations: Anti-TNF-alpha agent = anti tumor necrosis factor alpha agent, 5-ASA = 5-aminosalicylic acid
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spelling pubmed-46569592015-12-10 Septic knee arthritis in Crohn’s disease biological therapy-free patient. Case report Pop, C Calagiu, D Jantea, P Nemes, R J Med Life Case Presentations A 52-year-old woman with Crohn’s disease presented with septic arthrtis of the knee. This condition coincided with a symptomatic flare of her Crohn’s disease due to an ileal inflammatory stenosis, manifested as a phlegmonous mass palpable in the right lower quadrant and a small bowel obstruction. Results of synovial fluid cultures showed the presence of Gram-negative bacillus, Klebsiella pneumoniae and the CT scan images were highly suggestive of abdominal abscess within Crohn’s disease. The patient’s condition improved after following an antibiotic treatment and after the initiation of Anti-TNF-alpha agent Adalimumab, with no further exacerbation. Septic arthritis in Crohn’s disease should be considered to have a communicating source of sepsis consisting of an abdominal abscess or fistula. Abbreviations: Anti-TNF-alpha agent = anti tumor necrosis factor alpha agent, 5-ASA = 5-aminosalicylic acid Carol Davila University Press 2015 /pmc/articles/PMC4656959/ /pubmed/26664477 Text en ©Carol Davila University Press http://creativecommons.org/licenses/by/2.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Presentations
Pop, C
Calagiu, D
Jantea, P
Nemes, R
Septic knee arthritis in Crohn’s disease biological therapy-free patient. Case report
title Septic knee arthritis in Crohn’s disease biological therapy-free patient. Case report
title_full Septic knee arthritis in Crohn’s disease biological therapy-free patient. Case report
title_fullStr Septic knee arthritis in Crohn’s disease biological therapy-free patient. Case report
title_full_unstemmed Septic knee arthritis in Crohn’s disease biological therapy-free patient. Case report
title_short Septic knee arthritis in Crohn’s disease biological therapy-free patient. Case report
title_sort septic knee arthritis in crohn’s disease biological therapy-free patient. case report
topic Case Presentations
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4656959/
https://www.ncbi.nlm.nih.gov/pubmed/26664477
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