Cargando…
Identification of novel autophagic Radix Polygalae fraction by cell membrane chromatography and UHPLC-(Q)TOF-MS for degradation of neurodegenerative disease proteins
With its traditional use in relieving insomnia and anxiety, our previous study has identified onjisaponin B from Radix Polygalae (RP), as a novel autophagic enhancer with potential neuroprotective effects. In current study, we have further identified a novel active fraction from RP, contains 17 majo...
Autores principales: | Wu, An-Guo, Kam-Wai Wong, Vincent, Zeng, Wu, Liu, Liang, Yuen-Kwan Law, Betty |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657008/ https://www.ncbi.nlm.nih.gov/pubmed/26598009 http://dx.doi.org/10.1038/srep17199 |
Ejemplares similares
-
Onjisaponin B Derived from Radix Polygalae Enhances Autophagy and Accelerates the Degradation of Mutant α-Synuclein and Huntingtin in PC-12 Cells
por: Wu, An-Guo, et al.
Publicado: (2013) -
On-line identification of the chemical constituents of Polygoni Multiflori Radix by UHPLC-Q-ToF MS/MS
por: Wang, Xueting, et al.
Publicado: (2023) -
The New Application of UHPLC-DAD-TOF/MS in Identification of Inhibitors on β-Amyloid Fibrillation From Scutellaria baicalensis
por: Yu, Lu, et al.
Publicado: (2019) -
Intestinal Absorption Profile of Three Polygala Oligosaccharide Esters in Polygalae Radix and the Effects of Other Components in Polygalae Radix on Their Absorption
por: Ba, YinYing, et al.
Publicado: (2019) -
High-throughput screening for amyloid-β binding natural small-molecules based on the combinational use of biolayer interferometry and UHPLC−DAD-Q/TOF-MS/MS
por: Guo, Minsong, et al.
Publicado: (2022)