Cargando…
Chikungunya nsP2 protease is not a papain-like cysteine protease and the catalytic dyad cysteine is interchangeable with a proximal serine
Chikungunya virus is the pathogenic alphavirus that causes chikungunya fever in humans. In the last decade millions of cases have been reported around the world from Africa to Asia to the Americas. The alphavirus nsP2 protein is multifunctional and is considered to be pivotal to viral replication, a...
Autores principales: | Saisawang, Chonticha, Saitornuang, Sawanan, Sillapee, Pornpan, Ubol, Sukathida, Smith, Duncan R., Ketterman, Albert J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2015
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657084/ https://www.ncbi.nlm.nih.gov/pubmed/26597768 http://dx.doi.org/10.1038/srep17125 |
Ejemplares similares
-
Full length and protease domain activity of chikungunya virus nsP2 differ from other alphavirus nsP2 proteases in recognition of small peptide substrates
por: Saisawang, Chonticha, et al.
Publicado: (2015) -
Expression and biochemical characterization of nsP2 cysteine protease of Chikungunya virus
por: Pastorino, Boris A.M., et al.
Publicado: (2008) -
Targeting the nsp2 Cysteine Protease of Chikungunya Virus Using FDA Approved Library and Selected Cysteine Protease Inhibitors
por: Kumar, Prateek, et al.
Publicado: (2019) -
Role of Papain-Like Cysteine Proteases in Plant Development
por: Liu, Huijuan, et al.
Publicado: (2018) -
Structure determinants defining the specificity of papain-like cysteine proteases
por: Petushkova, Anastasiia I., et al.
Publicado: (2022)