Analysis of a Functional IL-6 Gene Polymorphism in HLAB27 Associated and Intermediate Uveitis Gives New Insight in Disease Pathogenesis and Commonality with Other Autoimmune Diseases

Purpose. Interleukin 6 (IL-6) plays a crucial role in both adaptive and innate immunity. The rs1800795 gene polymorphism of IL-6 is associated with various autoimmune diseases, like multiple sclerosis. Methods. 134 patients with HLAB27 positive iridocyclitis, 84 patients with intermediate uveitis, 1...

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Detalles Bibliográficos
Autores principales: Ewald, Lindner, Beate, Langner-Wegscheider, Stephanie, Sarny, Wilfried, Renner, Yosuf, El-Shabrawi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2015
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657109/
https://www.ncbi.nlm.nih.gov/pubmed/26640809
http://dx.doi.org/10.1155/2015/174062

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