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Early to Late Endosome Trafficking Controls Secretion and Zymogen Activation in Rodent and Human Pancreatic Acinar Cells

BACKGROUND & AIMS: Pancreatic acinar cells have an expanded apical endosomal system, the physiologic and pathophysiologic significance of which is still emerging. Phosphatidylinositol-3,5-bisphosphate [PI(3,5)P(2)] is an essential phospholipid generated by phosphatidylinositol 3-phosphate 5-kina...

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Detalles Bibliográficos
Autores principales:	Messenger, Scott W., Thomas, Diana D.H., Cooley, Michelle M., Jones, Elaina K., Falkowski, Michelle A., August, Benjamin K., Fernandez, Luis A., Gorelick, Fred S., Groblewski, Guy E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2015
Materias:	Original Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657148/ https://www.ncbi.nlm.nih.gov/pubmed/26618189 http://dx.doi.org/10.1016/j.jcmgh.2015.08.002

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