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Titration of mitochondrial fusion rescues Mff-deficient cardiomyopathy

Defects in mitochondrial fusion or fission are associated with many pathologies, raising the hope that pharmacological manipulation of mitochondrial dynamics may have therapeutic benefit. This approach assumes that organ physiology can be restored by rebalancing mitochondrial dynamics, but this conc...

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Detalles Bibliográficos
Autores principales:	Chen, Hsiuchen, Ren, Shuxun, Clish, Clary, Jain, Mohit, Mootha, Vamsi, McCaffery, J. Michael, Chan, David C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Research Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657172/ https://www.ncbi.nlm.nih.gov/pubmed/26598616 http://dx.doi.org/10.1083/jcb.201507035

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