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Regulating the regulator: Numb acts upstream of p53 to control mammary stem and progenitor cell

In this issue, Tosoni et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201505037) report that cell fate determinant and tumor suppressor Numb imposes asymmetric cell divisions in mammary stem cells by regulating p53. Numb thereby restricts mammary stem cell expansion and controls the prolif...

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Detalles Bibliográficos
Autores principales:	Faraldo, Marisa M., Glukhova, Marina A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Rockefeller University Press 2015
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657175/ https://www.ncbi.nlm.nih.gov/pubmed/26598611 http://dx.doi.org/10.1083/jcb.201510104

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