Transducing oxidative stress to death signals in neurons

Accumulation of reactive oxygen species (ROS) has been associated with aging and neurodegenerative diseases. Nevertheless, how elevated ROS levels cause neurodegeneration is unclear. In this issue, Wakatsuki et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201506102) delineate how oxidative...

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Detalles Bibliográficos
Autores principales: Cao, Xu, Fang, Yanshan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Rockefeller University Press 2015
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657176/
https://www.ncbi.nlm.nih.gov/pubmed/26572619
http://dx.doi.org/10.1083/jcb.201510105
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author Cao, Xu
Fang, Yanshan
author_facet Cao, Xu
Fang, Yanshan
author_sort Cao, Xu
collection PubMed
description Accumulation of reactive oxygen species (ROS) has been associated with aging and neurodegenerative diseases. Nevertheless, how elevated ROS levels cause neurodegeneration is unclear. In this issue, Wakatsuki et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201506102) delineate how oxidative stress is transduced into death signals, leading to neuronal apoptosis and axonal degeneration.
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spelling pubmed-46571762016-05-23 Transducing oxidative stress to death signals in neurons Cao, Xu Fang, Yanshan J Cell Biol Reviews Accumulation of reactive oxygen species (ROS) has been associated with aging and neurodegenerative diseases. Nevertheless, how elevated ROS levels cause neurodegeneration is unclear. In this issue, Wakatsuki et al. (2015. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201506102) delineate how oxidative stress is transduced into death signals, leading to neuronal apoptosis and axonal degeneration. The Rockefeller University Press 2015-11-23 /pmc/articles/PMC4657176/ /pubmed/26572619 http://dx.doi.org/10.1083/jcb.201510105 Text en © 2015 Cao and Fang This article is distributed under the terms of an Attribution–Noncommercial–Share Alike–No Mirror Sites license for the first six months after the publication date (see http://www.rupress.org/terms). After six months it is available under a Creative Commons License (Attribution–Noncommercial–Share Alike 3.0 Unported license, as described at http://creativecommons.org/licenses/by-nc-sa/3.0/).
spellingShingle Reviews
Cao, Xu
Fang, Yanshan
Transducing oxidative stress to death signals in neurons
title Transducing oxidative stress to death signals in neurons
title_full Transducing oxidative stress to death signals in neurons
title_fullStr Transducing oxidative stress to death signals in neurons
title_full_unstemmed Transducing oxidative stress to death signals in neurons
title_short Transducing oxidative stress to death signals in neurons
title_sort transducing oxidative stress to death signals in neurons
topic Reviews
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657176/
https://www.ncbi.nlm.nih.gov/pubmed/26572619
http://dx.doi.org/10.1083/jcb.201510105
work_keys_str_mv AT caoxu transducingoxidativestresstodeathsignalsinneurons
AT fangyanshan transducingoxidativestresstodeathsignalsinneurons

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