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Predicted binding site information improves model ranking in protein docking using experimental and computer-generated target structures

BACKGROUND: Protein-protein interactions (PPIs) mediate the vast majority of biological processes, therefore, significant efforts have been directed to investigate PPIs to fully comprehend cellular functions. Predicting complex structures is critical to reveal molecular mechanisms by which proteins...

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Detalles Bibliográficos
Autores principales: Maheshwari, Surabhi, Brylinski, Michal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657198/
https://www.ncbi.nlm.nih.gov/pubmed/26597230
http://dx.doi.org/10.1186/s12900-015-0050-4