Bacterial metabolites directly modulate farnesoid X receptor activity

BACKGROUND: The farnesoid X receptor (FXR), a ligand-activated transcription factor belonging to the adopted orphan receptor, plays an important role in maintaining health of the liver and intestine. In this study, we identified individual bacterial strains that directly modulated the activation of...

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Detalles Bibliográficos
Autores principales: Zhang, Xianqin, Osaka, Toshifumi, Tsuneda, Satoshi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2015
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657204/
https://www.ncbi.nlm.nih.gov/pubmed/26604978
http://dx.doi.org/10.1186/s12986-015-0045-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4657204/
https://www.ncbi.nlm.nih.gov/pubmed/26604978
http://dx.doi.org/10.1186/s12986-015-0045-y

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